Anywhere from a quarter to half of physicians worldwide are estimated to experience job burnout. General internal medicine and family medicine—the specialties for most adult hospitalists—claim some of the highest rates of physician burnout in the United States. Within the adult generalist fields, several studies suggest clinic-based primary care physicians report burnout more frequently than their inpatient peers, but hospitalists remain among the physicians most susceptible to job burnout. This white paper offers insights into what causes burn out in hospitalists and steps they can take to avoid it.