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Harrison's 22nd edition:
the voice of clinical reason

The gold standard in medical education and knowledge, updated for 2025 and beyond - now exclusively available on AccessMedicine.

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Harrisons 21st Edition

Support student success. Simplify your teaching.

With a trusted resource built for both the classroom and the clinic.


  • Save time with ready-to-use content designed to integrate seamlessly into your teaching
  • Boost student confidence with clinically relevant cases and the latest internal medicine updates
  • Rely on a proven, authoritative text that supports academic excellence and real-world readiness

What's new in Harrison's 22nd edition?

The 22nd edition introduces brand new chapters and refreshed content, delivering the most current, curriculum-aligned insights for modern medical education.

10+ brand new chapters

covering emerging issues shaping modern medicine

Updated content

reflecting new approved therapeutics, practice-changing guidelines, and evidence summaries

Expanded editorial team

bringing fresh perspective to the renowned panel

Get a sneak peek at what's inside and why it's vital for your curriculum

Trusted by institutions worldwide

For academic institutions

Real-time updates and continuous learning

For academic institutions

Interactive tools and self-assessment features on AccessMedicine

For companies providing care

Used across hundreds of medical schools globally

Explore Harrison's 22nd edition on AccessMedicine with 14 days of complimentary access. Sign up below: