Harrison's 22nd edition:
the voice of clinical reason
The gold standard in medical education and knowledge, updated for 2025 and beyond - now available to pre-order.
Medicine moves fast. So should you.
Clinicians rely on Harrison’s Principles of Internal Medicine for:
- Up-to-date clinical content from the best minds in medicine
- Evidence-based practices and emerging treatments for reference
- Aligning care with current standards – across every specialty
- A go-to resource for clear, authoritative answers at the point of care
What's new in Harrison's 22nd edition?
The latest edition delivers fully updated content and new chapters to support real-world clinical decisions.
10+ brand new chapters
covering emerging issues shaping modern medicineUpdated content
that reflects new approved therapeutics and new practice-changing guidelines and evidence summariesExpanded editorial team
bringing fresh perspective to Harrison’s renowned panel
Take a closer look at why Harrison’s remains essential
Featured blog:
AI in the clinic: 6 essential machine learning tools healthcare professionals should know
Free chapter:
Preview updated chapter: The Value of the Physical Examination in Modern Medicine
Trusted by professionals and institutions worldwide
70+ years of clinical authority
Digital convenience for modern curricula
Real-time updates and continuous learning
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